The Myotubular Trust is delighted to announce a fourth successive year of making substantial research grants to help find a treatment or cure for myotubular and centronuclear myopathy. Following a rigorous application and peer review process, our Scientific Advisory Board recommended that this year’s grant goes to a joint team of Dr Heinz Jungbluth at King’s College, London, UK and Dr Susan Treves who heads the Muscle Research group at Basel University Hospital, Switzerland.
Although a lot of work has been done in identifying the genes that cause myotubular and centronuclear myopathy, the precise way in which those genetic faults cause muscle weakness, and other complications, is just not understood. To understand this ‘why’ will be a huge step in developing a cure or treatment.
Recent research findings have suggested two very promising lines of further investigation that may tell us something fundamental about these conditions, and Drs Jungbluth and Treves will investigate them both. The first is the link between myotubular and centronuclear myopathy and the processes that cause muscles to contract, in particular the process of releasing calcium into muscle cells. The second is a link between the “recycling” mechanism in cells and certain genes that cause myotubular and centronuclear myopathy. You can read more about the research here.
We are delighted to be funding these very exciting lines of investigation, being carried out by this very impressive team of researchers.